Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof

摘要

The present invention relates to a compound having formula (I): wherein: —X is in particular ¹²⁵I Or ²¹¹At; —R₁ and R′₁ are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; —R₂ is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; —Z is a heteroatom, R₅, R₈ and R₉ are preferably H; —Y is preferably an electron withdrawing group.;