首页> 外国专利> Compound of (6S, 9aS) - N - Benzyl - 6 - (4-hydroxyphenyl) methyl - 4.7 - 8 - ({2 - 3 - (piperazin-1-yl) azetidin - triazin-1-yl pyridin-2-yl) methyl) - 2 - (prop - 2 - in - 1 - il) - octahidro - 1H - 2.1 - pirazino c 1,2,4 triazine - 1 - carboxamide

Compound of (6S, 9aS) - N - Benzyl - 6 - (4-hydroxyphenyl) methyl - 4.7 - 8 - ({2 - 3 - (piperazin-1-yl) azetidin - triazin-1-yl pyridin-2-yl) methyl) - 2 - (prop - 2 - in - 1 - il) - octahidro - 1H - 2.1 - pirazino c 1,2,4 triazine - 1 - carboxamide

机译:(6S,9aS)-N-苄基-6-[(4-羟苯基)甲基]-4.7-[8-({2-[3-(哌嗪-1-基)氮杂环丁烷-三嗪-1-基]吡啶-2-基)甲基)-2-(prop-2-in-1-il)-辛杂-1H-2.1-吡嗪醇[c] [1,2,4]三嗪-1-羧酰胺

摘要

A compound represented by the formula (1) or a pharmaceutically acceptable salt thereof: where R¹ is a C₁₋₆ alkyl group; R² and R³ are the same or different from each other and each is a hydrogen atom or a C₁₋₆ alkyl group; X², X³ and X⁴ are the same or different from each other and each is a hydrogen atom or a halogen atom; and X⁵ is a hydrogen atom or -P (= O) (OH) ₂, has a Wnt pathway modulation activity.
机译:式(1)表示的化合物或其药学上可接受的盐:其中R 1为C 1-8烷基; R 2和R 3彼此相同或不同,分别为氢原子或C 1-8烷基。 X 2,X 3和X 4彼此相同或不同,分别为氢原子或卤素原子。 X 1是氢原子或-P(= O)(OH)2,具有Wnt途径调节活性。

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