identification, evaluation and therapy of cancer with congenital or acquired resistance to alk inhibitors.

摘要

identification, evaluation and therapy of cancer with congenital or acquired resistance to alk inhibitors. The present invention relates to compositions, kits and methods for determining whether individuals with an alk mutation-positive cancer (s) are likely to respond to treatment with an alk inhibitor and / or if a patient with such cancer (s) is likely to have slower progression of the disease. Methods for prognosis of a disease duration time in an individual who has such cancer are further described.