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'2- (arylamino) -3h-imidazo 4,5-b pyridine-6-carboxamide derivatives, and pharmaceutical composition'

机译:“ 2-(芳基氨基)-3h-咪唑并[4,5-b]吡啶-6-羧酰胺衍生物和药物组合物”

摘要

2- (Arylamino-3h-imidazo [4,5-b] pyridine-6-carboxamide derivatives and their use as mp-ges-1 inhibitors. This invention relates to the compounds of formula I: their use as inhibitors of mp-ges-1. prostaglandin and microsomal synthase-1 (mp-ges-1), pharmaceutical compositions containing it, and their use as medicaments for the treatment and / or prevention of inflammatory diseases and associated conditions. 1 ^, r ^ 2 ^, r ^ 6 ^, r ^ 7 ^ have meanings given in the description.
机译:2-(芳氨基-3h-咪唑并[4,5-b]吡啶-6-羧酰胺衍生物及其作为mp-ges-1抑制剂的用途。本发明涉及式I化合物:其作为mp-ges抑制剂的用途。 -1。前列腺素和微粒体合酶-1(mp-ges-1),包含它们的药物组合物及其在治疗和/或预防炎症性疾病及相关病症中的用途1 ^,r ^ 2 ^,r ^ 6 ^,r ^ 7 ^具有描述中给出的含义。

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