首页> 外国专利> Modelling the action of one optical fiber in a treatment for photodynamic therapy and assistance for the planning of such treatment.

Modelling the action of one optical fiber in a treatment for photodynamic therapy and assistance for the planning of such treatment.

机译:对一种光纤在光动力疗法的治疗中的作用进行建模,并协助规划这种治疗。

摘要

Modelling the action of one optical fiber in a treatment for photodynamic therapy and assistance for the planning of such treatment.The invention relates to a method (200) that provides assistance in planning the treatment of a patient with photodynamic therapy in a patient with treatment planning of photodynamic therapy.During which a photosensitive substance default should be administered in the patient and subsequently subjected to a light in a wave length preset by a number of optical fibers which can be inserted into a length of insertion in the area to be works of ACO RDO with affixed in relation to a grid of brachytherapy.The method comprises: the madiu00e7u00e3o (230) of the volume of the area to be treated by reconstruction of the volume on the basis of digital processing of contour inserted directly into a series of images digital processing of the area to be treated; and subsequently, on the basis of the calculation of the nu00famer The optical fibres to be used.Determine (250) the position of the optical fibers in relation to the grade of brachytherapy and the length of insertion of the same, which improves the correspondence between a total volume of action theoretical calculated and the measured volume of the area to be treated.The said volume of total action theoretical calculated as a function of the position of each fiber and a volume of theoretical elementary action of a fiber which corresponds to the volume of a cylinder that has height and radius of action predetermined r that correspode the length of insertion of the fiber.The invention also relates to a method for model 9100) the radius of action of one optical fiber with the use of a correlation of measured volumes of necrosed areas actually following a plurality of clinical trials carried out in different patients with the theoretical calculated in volumes. The basis of the same sets of parameters as those used in clinical trials and the volume of the action theorist heParliamentary one fiber.
机译:对一种光纤在用于光动力疗法的治疗中的作用进行建模并协助规划这种治疗。本发明涉及一种方法(200),该方法(200)在具有治疗计划的患者中协助规划以光动力疗法治疗患者。在此期间应在患者体内给予默认的光敏物质,然后使其受到由许多光纤预置的波长的光的影响,这些光纤可以插入ACO工作区域的插入长度内相对于近距离放射治疗网格贴附的RDO。该方法包括:根据直接插入轮廓线中的轮廓的数字处理,通过重建体积来处理要治疗区域的体积(230)。对要治疗的区域进行一系列图像数字处理;然后在计算n的基础上使用所要使用的光纤。确定(250)光纤相对于近距离放射治疗的等级和其插入长度的位置,从而改善所述理论上的总作用量与待处理区域的测量体积之间的对应关系。所述理论上的总作用量根据每根纤维的位置和相应于纤维的理论上的基本作用量而计算本发明还涉及一种用于模型9100)的方法,该方法使用以下关系式来计算一根光纤的作用半径:在对不同患者进行了多项临床试验后,实际上测量了坏死区域的体积,并以体积为理论计算值。与临床试验中使用的参数相同的一组参数的基础,以及行动理论家heParliamentary一根纤维的体积。

著录项

  • 公开/公告号BR112013005574A2

    专利类型

  • 公开/公告日2016-05-10

    原文格式PDF

  • 申请/专利权人 STEBA MAOR SA;

    申请/专利号BR20131105574

  • 申请日2011-09-06

  • 分类号A61N5/06;

  • 国家 BR

  • 入库时间 2022-08-21 14:27:17

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