首页> 外国专利> dietary nutrient or food supplement comprising an edible composition as well as an orally administrable pharmaceutical composition and uses thereof

dietary nutrient or food supplement comprising an edible composition as well as an orally administrable pharmaceutical composition and uses thereof

机译:包含可食用组合物以及口服药物组合物的饮食营养或食品补充剂及其用途

摘要

"Phytosterol esters enriched oils and diacylglycerols for use in lowering cholesterol and triglycerides." The present invention relates to the use of a composition comprising a combination of diacylglycerol (s) (dag), mainly 1,3-diacylglycerol (s) and phytostanol ester and / or phytosterol (pse) dissolved or dispersed in edible oil and / or edible fat, particularly olive oil, canola oil and fish, in the manufacture of orally administrable nutritional supplements and pharmaceutical preparations which are capable of lowering blood levels of cholesterol and triglycerides alike and / or to decrease blood levels. serum, ldl in serum and macrophage oxidation, inhibiting foam cell formation and / or preventing the harmful effects generated by lipid-induced oxidative stress. furthermore, the composition of the invention as well as pharmaceutical preparations thereof is suitable for the treatment and prevention of atherosclerosis-related conditions such as cardiovascular disease (cvd), coronary heart disease (chd) and diabetes mellitus.
机译:“植物甾醇酯富含油和二酰基甘油,可用于降低胆固醇和甘油三酸酯。”本发明涉及组合物的用途,所述组合物包含溶解或分散在食用油和/或中的二酰基甘油(dag),主要是1,3-二酰基甘油和植物甾烷醇酯和/或植物甾醇(pse)的组合。可口服的营养补品和药物制剂的生产中的食用脂肪,特别是橄榄油,低芥酸菜子油和鱼,它们能够降低胆固醇和甘油三酸酯的血药浓度和/或降低血药浓度。血清,血清中的Idl和巨噬细胞氧化,抑制泡沫细胞形成和/或防止脂质诱导的氧化应激产生有害作用。此外,本发明的组合物及其药物制剂适用于治疗和预防与动脉粥样硬化有关的病症,例如心血管疾病(cvd),冠心病(chd)和糖尿病。

著录项

  • 公开/公告号BRPI0407338B1

    专利类型

  • 公开/公告日2016-10-25

    原文格式PDF

  • 申请/专利权人 ENZYMOTEC LTD.;

    申请/专利号BR2004PI07338

  • 发明设计人 AVIDOR SHULMAN;DORI PELLED;DORIT PLATT;

    申请日2004-02-10

  • 分类号A23D9/013;A23L1/30;A61K31/20;A61K31/23;A61K31/56;A61K31/575;A61K45/06;A61P9;

  • 国家 BR

  • 入库时间 2022-08-21 14:26:58

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