method for modulating neoplastic growth, uses of a compound or a pharmaceutically acceptable salt, ester or prodrug thereof, a vascular endothelial growth factor binder, and a taxane, pharmaceutical formulation, and kit

摘要

The present invention relates to combinations of compounds such as compounds of the xanthenone acetic acid class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and vascular endothelial growth factor binders, in particular the monoclonal antibody Avastin (bevacizumab). More particularly, the invention is concerned with the use of such combinations in the treatment of cancer and pharmaceutical formulations containing such combinations.