'method for regulating metalloproteinase 9 (mm9) activity, method for identifying an agent capable of specifically regulating mmp-9, method of treating the clinical condition mediated by mmp-9, a molecule capable of specifically regulating mmp-9 activity , humanized antibody and pharmaceutical composition '

摘要

A method of regulating an activity of metalloproteinase 9 (MMP-9) is disclosed. The method comprises containing the MMP-9 with an agent which specifically interacts with an OG domain of the MMP-9. Molecules capable of specifically interacting with the OG domain, methods of identifying same, pharmaceutical compositions comprising same and uses thereof are also disclosed.