Biologically compatible smart nanotherapeutic for prevention and therapy of carcinoma metastatic states by inactivation of tumor exosomes and process for preparing thereof

摘要

hollow spherical nano particles with makrootvory on outer diameter of between 200 and 400 nm, the average makrootvoru nanoparticles between 50 to 700 nm, 0 to 100 makrodifusnu00edch openings with a diameter in the range of 10 to 50 nm, difusnu00edch channels for effective area of 0.4 to 9 nm.sup.2.n.each of the difusnu00edch channels, the armor of covalently coupled polymer of trojdimenzionu00e1lnu011b cross-linked carbohydrate units comprising 1 to 50 isocentricku00fdch layers of polysaccharide and whose way of degree, as well as the type of cross - linkage drives the speed of biodegradation (meta bolizace) nanoparticles in the organism and thus form the so-called.the nanozu00e1mek and inner wall of nanoparticles is covalently modified biocides (exoxomicidy) or, generally, substances with antiexosomu00e1lnu00edm and antimetastaticku00fdm effect is prepared by polycondensation of carbohydrate units zesu00edu0165ovacu00edmi linkery.the biocides on the inner wall of antiexosomu00e1lnu011b / antimetastaticky skeletal nanoparticles is effective nanoterapeutikum suppressing the growth and spread of the antiexosomu00e1lnu011b / antimetastaticky effective nanoterapeutikum suppressing the growth and spread of the dividing regardless of you pu tumour and especially eliminating the possibility of metastasis.