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HETEROCYCLIC COMPOUNDS AS HEDGEHOG SIGNAL PATH INHIBITORS

机译:杂环化合物作为刺猬信号通路的抑制剂

摘要

The present invention relates to new compounds. The compounds according to the invention are agonists of the Hedgehog signaling pathway. In particular, the compounds according to the invention are used as Smoothened agonists (SMO). The invention also contemplates the use of compounds for treating diseases amenable to treatment by inhibiting the Hedgehog signaling pathway and SMO, for example cancer.
机译:本发明涉及新化合物。根据本发明的化合物是刺猬信号通路的激动剂。特别地,根据本发明的化合物用作平滑化激动剂(SMO)。本发明还考虑了化合物通过抑制刺猬信号通路和SMO例如癌症来治疗适于治疗的疾病的用途。

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