Potent larvicidal phytoconstituents from petroleum ether extract of dried fruits of carissa carandas

摘要

Potent larvicidal phytoconstituents from petroleum ether extract of dried fruits of Carissa carandas The mosquito larvicidal activities of petroleum ether crude extract of dried fruits of Carissa carandas was examined against the larvae of Cx. quinquefasciatus and A. aegypti. 100 % mortality was recorded on the basis of LC50 and LC90. The extract showed LC50 = 116.14±2.26 mg/mL; LC9o=464.18±26.32mg/mL against the larvae of A. aegypti and (LC50=210.36±4.68 mg/mL; LC90= 672.30±38.69 mg/mL against the larvae of Cx. quinquefasciatus respectively. The GC-MS analysis of the petroleum ether extract revealed the presence of nine compounds. Out of which p-Caryophyllene, a natural bicyclic sesquiterpenes was isolated from the non polar fraction of dried fruits of Carissa carandas. Keywords: Carissa carandas, larvicidal activity, petroleum ether extract, GC-MS, P-Caryophyllene