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A method for the production of cyclopropane derivatives.

机译:一种生产环丙烷衍生物的方法。

摘要

A process for the preparation of cyclopropane derivatives useful as chemical intermediates in the preparation of agricultural products, said process comprising a. preparing Grignard reagent by treating the compound of formula (I) with Magnesium turning in dry solvent under in an inert atmosphere at reflux temperature; b. preparing compound of formula (III) by treating the Grignard reagent with aldehyde of formula (II) in presence of dry solvent at reflux temperature to obtain the compound of formula (III); and c. preparing compound of formula (IV) by subjecting the compound of formula (III) to oxidation in presence of catalyst and solvent to obtain the compound of formula (III); Wherein X : -C1 (Chloro), Br (Bromo), I (1odo), etc and R1 is C1 to C5 straight or branched chain aliphatic alkyl group.
机译:一种用于制备农产品中的化学中间体的环丙烷衍生物的方法,所述方法包括:在惰性气氛中,在回流温度下,在干燥溶剂中用镁处理式(I)化合物,用镁处理,制备格氏试剂; b。通过在干燥溶剂存在下于回流温度下用式(II)的醛处理格氏试剂来制备式(III)的化合物,得到式(III)的化合物。和c。在催化剂和溶剂的存在下,通过使式(III)的化合物氧化,制备式(IV)的化合物,得到式(III)的化合物。其中X:-C1(氯),Br(溴),I(1odo)等,R1为C1-C5直链或支链脂族烷基。

著录项

  • 公开/公告号IN2014MU01309A

    专利类型

  • 公开/公告日2015-11-20

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN1309/MUM/2014

  • 发明设计人 HIREMATH ASHOK;DHAKANE VALMIK;

    申请日2014-04-09

  • 分类号A61K9/00;

  • 国家 IN

  • 入库时间 2022-08-21 14:25:17

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