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Indian bicycle heterogeneity analogy as ror modulator

机译:印度自行车异质性作为ror调节剂

摘要

The invention relates to formula compound (I) and pharmaceutically acceptable salts, wherein X, X1 are n or CH, M is - o-o-co,R2, R3 and R4 include halogen, R5 is h or C1-C4 tar, M is 0-3, n is 0-3, P is 0-4. These are modulators related to retina of active gamma-t huerfano (roryt) receiver. These compounds prevent, inhibit, or inhibit Rorty's effects and can therefore be used to treat Rorty's diseases, diseases, symphonies, or moderate diseases such as pain, inflammation, mumps, asthma, rheumatoid arthritis, colitis, multiple sclerosis, neurodegenerative diseases, and cancer.
机译:本发明涉及式化合物(I)及其药学上可接受的盐,其中X,X 1为n或CH,M为-oo-co,R 2,R 3和R 4包括卤素,R 5为h或C 1 -C 4焦油,M为0。 -3,n为0-3,P为0-4。这些是与活性伽马-t huerfano(roryt)接收器的视网膜相关的调制器。这些化合物可预防,抑制或抑制Rorty的作用,因此可用于治疗Rorty的疾病,疾病,交响乐或中度疾病,例如疼痛,炎症,腮腺炎,哮喘,类风湿性关节炎,结肠炎,多发性硬化症,神经退行性疾病和癌症。

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