IL1RAP expression in acute and chronic myeloid leukemia cells

摘要

An agent comprising or consisting of an antibody with specificity for the accessory protein of interleukin 1 receptor (IL1RAP) for use in the treatment of leukemia, the agent being capable of inducing antibody-dependent cell-mediated cytotoxicity (ADCC) of pathological hemocytoblasts and / or progenitor cells associated with leukemia, where the cells express IL1RAP.