首页> 外国专利> A process for the preparation of (3aR, 4S, 6R, 6aS) -6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta d 1,3 dioxol-4-ol dibenzoyl-L-tartrate and products said process

A process for the preparation of (3aR, 4S, 6R, 6aS) -6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta d 1,3 dioxol-4-ol dibenzoyl-L-tartrate and products said process

机译:(3aR,4S,6R,6aS)-6-氨基-2,2-二甲基四氢-3aH-环戊五[d] [1,3]二氧杂-4-醇二苯甲酰基-L-酒石酸盐的制备方法和产物处理

摘要

A process for preparing a diastereomerically pure dibenzoyl-L-tartrate salt of a compound of formula (III) ** Formula ** comprising the steps of (a) mixing a racemic compound of formula (II) ** Formula ** with enantiomerically pure dibenzoyl-L-tartaric acid or its monohydrate to form a diastereoisomeric salt, wherein the solvent is a mixture of water and ethanol; and (b) crystallize said salt.
机译:制备式(III)**式**化合物的非对映体纯的二苯甲酰基-L-酒石酸盐的方法,包括以下步骤:(a)将式(II)**式**的外消旋化合物与对映体纯二苯甲酰基-L-酒石酸或其一水合物形成非对映异构体盐,其中溶剂为水和乙醇的混合物; (b)使所述盐结晶。

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