首页> 外国专利> Novel anti-aging peptides and cosmetic and / or pharmaceutical composition containing them

Novel anti-aging peptides and cosmetic and / or pharmaceutical composition containing them

机译:新型抗衰老肽和含有它们的化妆品和/或药物组合物

摘要

Peptide compound of the following general formula (I): R1-X1-X2-Ser-Pro-Leu-Gln-X3-X4-R2 in which, X1 represents a cysteine, a methionine, or is equal to zero X2 represents a serine , a threonine, or is equal to zero, X3 represents an alanine, a glycine, an isoleucine, a leucine, a proline, a valine or is equal to zero, X4 represents an asparagine, a glutamine, or is equal to zero. R1 represents the primary amine function of the N-terminal amino acid, free or substituted by a protecting group that may be selected from an acetyl group, a benzoyl group, a tosyl group or a benzyloxycarbonyl group, R2 represents the hydroxyl group of the carboxyl function of the C-terminal amino acid, free or substituted by a protecting group that may be selected from a C1 to C20 alkyl chain, or an NH2, NHY or NYY group in which Y represents a C1 to C4 alkyl chain, said sequence being constituted of general formula (I) for 4 to 8 amino acid residues.
机译:以下通式(I)的肽化合物:R1-X1-X2-Ser-Pro-Leu-Gln-X3-X4-R2其中,X1代表半胱氨酸,蛋氨酸或等于零X2代表丝氨酸,苏氨酸或等于零,X3代表丙氨酸,甘氨酸,异亮氨酸,亮氨酸,脯氨酸,缬氨酸或等于零,X4代表天冬酰胺,谷氨酰胺或等于零。 R 1代表N端氨基酸的伯胺官能团,其自由或被保护基取代,该保护基可以选自乙酰基,苯甲酰基,甲苯磺酰基或苄氧羰基,R 2代表羧基的羟基C端氨基酸的功能,其自由或被保护基取代,该保护基可以选自C1至C20烷基链,或其中Y表示C1至C4烷基链的NH2,NHY或NYY基团,所述序列为由通式(I)构成的4至8个氨基酸残基。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号