POLYMER FOR USE IN CONDUITS, MEDICAL DEVICES AND BIOMEDICAL SURFACE MODIFICATION

摘要

A copolymer comprising (a) one or more pendant group segments and (b) one ormore polyol segments, each of said segments being linked to one or morefurther segments, and one or more of the pendant group segments being selectedfrom: (i) siloxane segments; (ii) segments containing phosphoryl choline or aderivative or analogue thereof; (iii) segments containing a di- ortrifluoromethyl group; (iv) heparin-like segments containing a group offormula: (XII) D-N=N-Ar-SO3- (v) segments containing a group of formula: (I)[P]n~-[Lys]n-Lys-[Spacer]-Lys-[Al]x in which D, Ar, P, Lys, Al, Spacer, x, nand n~ are as defined herein, and wherein at least a part of each of saidpendant group segment(s) is on a side chain of the copolymer. The copolymer isuseful in the production of implantable devices such as vascular grafts.