METHODS AND SYSTEMS FOR SOLUTION BASED SEQUENCE ENRICHMENT AND ANALYSIS OF GENOMIC REGIONS

摘要

The present invention provides novel methods and systems for capturing andenrichment of target nucleic acids forreducing the complexity of target nucleic acids, preferably a genomic sample,for further analysis such as direct DNA sequencing,resequencing or SNP calling. In particular, the present invention provides forthe enrichment of targeted sequences in a solutionbased format.