ENZYMATIC SYNTHESIS PROCESS FOR (7S) 3,4-DIMETHOXYBICYCLO4.2.0OCTA-1,3,5-TRIENE 7-CARBOXYLIC ACID OR OF ITS ESTERS AND APPLICATION OF IVABRADINE AND ITS SALTS TO THE SYNTHESIS

摘要

Process for the enzymatic synthesis of the compound of formula (I): (see formula I) in which R1 represents a hydrogen atom or an alkyl group. Application to the synthesis of ivabradine and its addition salts with a pharmaceutically acceptable acid.