首页> 外国专利> AGENT TO PROMOTE THE CELL-SURFACE EXPRESSION OR AGENT TO INHIBIT THE CELL-SURFACE EXPRESSION OF PHOSPHATIDYLSERINE, AND AGENT TO INHIBIT THE FORMATION OF LIPID RAFT CLUSTERS

AGENT TO PROMOTE THE CELL-SURFACE EXPRESSION OR AGENT TO INHIBIT THE CELL-SURFACE EXPRESSION OF PHOSPHATIDYLSERINE, AND AGENT TO INHIBIT THE FORMATION OF LIPID RAFT CLUSTERS

机译:促进细胞表面表达的代理商或抑制磷脂酰丝氨酸的细胞表面表达的代理商,并抑制脂质筏簇的形成

摘要

Provided are: an agent that promotes the cell surface expression of PS, and that includes a peptide containing the EGF1 domain of factor IX or a peptide containing the EGF3 domain of endothelial cell-1 protein; an agent that inhibits the cell surface expression of PS, and that contains a peptide that includes a portion obtained by removing the trypsin domain (heavy chain) portion and the light chain portion from the full length of factor IX; and an agent for inhibiting the formation of lipid raft clusters, and that contains a peptide that includes a portion obtained by removing the trypsin domain (heavy chain) portion and the light chain portion from the full length of factor IX.
机译:提供:促进PS的细胞表面表达的试剂,其包括含有因子IX的EGF1结构域的肽或含有内皮细胞1蛋白的EGF3结构域的肽;和抑制PS的细胞表面表达的试剂,其包含肽,该肽包含通过从因子IX的全长除去胰蛋白酶结构域(重链)部分和轻链部分而获得的部分。含有肽的肽,该肽包含通过从因子IX的全长除去胰蛋白酶结构域(重链)部分和轻链部分而获得的部分。

著录项

  • 公开/公告号WO2015170778A1

    专利类型

  • 公开/公告日2015-11-12

    原文格式PDF

  • 申请/专利权人 NIHON UNIVERSITY;

    申请/专利号WO2015JP63840

  • 申请日2015-05-07

  • 分类号A61K38/46;A61K38;A61K39/395;A61K49;A61P31/12;A61P35;A61P43;

  • 国家 WO

  • 入库时间 2022-08-21 14:20:43

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