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Methods and compositions for treatment of muscle wasting, muscle weakness, and/or cachexia

机译:用于治疗肌肉消瘦,肌肉无力和/或恶病质的方法和组合物

摘要

Embodiments of the invention include methods of treating, preventing, and/or reduce the risk or severity of a condition selected from the group consisting of muscle wasting, muscle weakness, cachexia, and a combination thereof in an individual in need thereof. In some embodiments, particular small molecules are employed for treatment, prevention, and/or reduction in the risk of muscle wasting. In at least particular cases, the small molecules are inhibitors of STAT3.
机译:本发明的实施方案包括在有需要的个体中治疗,预防和/或降低选自由肌肉萎缩,肌肉无力,恶病质及其组合组成的组的病症的风险或严重性的方法。在一些实施方案中,将特定的小分子用于治疗,预防和/或减少肌肉萎缩的风险。在至少特定的情况下,小分子是STAT3的抑制剂。

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