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A METHOD FOR PROTECTING LIVER AND A LIVER PROTECTING AGENT

机译:一种保护肝的方法和保护肝的剂

摘要

An object of the present invention is to provide a protective method for liver comprising the administration of an extract from inflamed tissues inoculated with vaccinia virus to a patient who needs the treatment and to provide a liver protective agent, etc. where such an extract is an active ingredient. In the present invention, it has been recognized that, in hepatocytes, activation of NF- B, expression of NF- B target genes, activation of JNK, apoptosis and fat accumulation can be inhibited or suppressed. The agent containing the extract as an active ingredient is a drug exhibiting less adverse action and high safety. Accordingly, the present invention provides very useful protective method for liver and liver protecting agent.
机译:本发明的目的是提供一种肝脏保护方法,该方法包括将接种牛痘病毒的发炎组织的提取物给予需要治疗的患者,并提供肝脏保护剂等,其中所述提取物为有效成分。在本发明中,已经认识到,在肝细胞中,可以抑制或抑制NF-B的活化,NF-B靶基因的表达,JNK的活化,细胞凋亡和脂肪积聚。含有提取物作为有效成分的药剂是副作用少且安全性高的药物。因此,本发明提供了非常有用的肝脏保护方法和肝脏保护剂。

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