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FEMALE SILKWORM LETHAL STRAIN OF BOMBYX MORI

机译:桑比蚕的女性家蚕丝状应变

摘要

Established and provided is a strain of an insect belonging to the order Lepidoptera, said strain being able to be easily maintained and managed without interrupting the genetic background thereof, being applicable to genetic modification technology and easily and arbitrarily allowing male-specific breeding within a short period of time.A female lethal strain can be obtained by transferring a gene expression vector, said gene expression vector encoding a mutated Masc gene that has cleavage resistance against Fem piRNA-Siwi complex and maintains the activity of the wild type Masc gene, into an insect belonging to the order Lepidoptera.
机译:建立并提供了一种属于鳞翅目的昆虫品系,所述品系能够容易地维持和管理而不会中断其遗传背景,适用于基因修饰技术并且容易且任意地允许在短时间内繁殖雄性。可以通过将基因表达载体转移到属于该昆虫的基因中,该基因表达载体编码具有对Fem piRNA-Siwi复合物具有切割抗性并保持野生型Masc基因的活性的突变的Masc基因,该女性表达菌株可以得到女性致死菌株。订购鳞翅目

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