A PHARMACEUTICAL FORMULATION COMPRISING RESVERATROL, BENFOTIAMINE AND PYRIDOXAMINE, A PROCESS OF MAKING IT AND A METHOD OF TREATMENT USING IT

摘要

The invention relates to a stable oral liquid formulation developed for treating negative effects of Advanced Glycation end Products (AGEs) in a clear oral liquid formulation containing Resveratrol, Benfotiamine, Pyridoxamine and one or more pharmaceutically active agents in a suitable vehicle and an effective amount of solubilizer. The solubilizer may include Povidone, Polyoxyl 40 hydrogenated castor oil but not limited to these wherein the solubilizer enhances solubility of Resveratrol in water and stabilizes the Benfotiamine and Pyridoxamine in the formulation along with Resveratrol. The process of making the formulation is unique. It may be used for treatment and prevention of conditions and diseases including many degenerative diseases, such as diabetes, atherosclerosis, chronic renal failure caused due to AGEs and formation of Advanced Lipoxidation End Products (ALEs).