首页> 外国专利> GENETIC MARKER FOR DETERMINING PATHOGENICITY OF STREPTOCOCCUS INIAE AND KIT FOR EXAMINING DETERMINANT MARKERS OF PATHOGENICITY BY USING PEPTIDE NUCLEIC ACID

GENETIC MARKER FOR DETERMINING PATHOGENICITY OF STREPTOCOCCUS INIAE AND KIT FOR EXAMINING DETERMINANT MARKERS OF PATHOGENICITY BY USING PEPTIDE NUCLEIC ACID

机译:用肽核酸测定链球菌INIAE 的致病性的遗传标记和检查致病性决定性标志的试剂盒

摘要

The present invention relates to a probe for determining a genotype of Steptococcus iniae, the probe being capable of hybridizing, under strict conditions, with a sequence fragment containing a single nucleotide polymorphism variation of T368C or T385G in the cpsD sequence, which is represented by SEQ ID NO: 1, of Streptococcus iniae and, more particularly, to a kit which allows each genotype influencing pathogenicity to have different melting temperature by using a peptide nucleic acid (PNA) having an excellent binding ability to DNA, thereby enabling a simple, rapid, and accurate determination of the pathogenicity of S. iniae.
机译:本发明涉及一种确定 Stepcococcus iniae 的基因型的探针,该探针能够在严格条件下与cpsD中含有T368C或T385G的单核苷酸多态性变异的序列片段杂交。序列,该序列由链球菌的SEQ ID NO:1表示,更具体地说,涉及一种试剂盒,该试剂盒通过使用肽核酸(PNA)使每种影响致病性的基因型具有不同的解链温度具有对DNA的优异结合能力,从而能够简单,快速,准确地确定 S的致病性。 iniae

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