The invention relates to an immunotherapeutic vaccine for the treatment of infections by HPV16 or HPV18 or both HPV16 and HPV18 when the treated subject is selected from the group of human subjects infected with HPV16 or HPV18 or both (HPV16 and/or HPV18) and having no premalignant genital lesions related to said HPV(s), in particular no premalignant cervical lesions, and especially having no cancer related to said HPV infections, in particular no carcinomas related to said HPV infection.
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