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USE OF NANOPARTICLES COATED WITH RED BLOOD CELL MEMBRANES TO ENABLE BLOOD TRANSFUSION
USE OF NANOPARTICLES COATED WITH RED BLOOD CELL MEMBRANES TO ENABLE BLOOD TRANSFUSION
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机译:使用涂有红色血液细胞膜的纳米颗粒来实现输血
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摘要
The present invention relates to methods, combinations and pharmaceutical compositions for supplying a blood source from a donor source with a mis-matched blood type, or potentially a mis-matched blood type, to a recipient, using, inter alia, an effective amount of a nanoparticle comprising a) an inner core comprising a non-cellular material, and b) an outer surface comprising a cellular membrane derived from a red blood cell, the cellular membrane of the nanoparticle comprising a blood type antigen that exists on the red blood cell from the donor source, but is missing or potentially missing on red blood cells of the recipient.
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