The present invention relates to a method for analyzing activity of human mutant phenylalanine hydroxylase (PAH) using cellular slime molds and, specifically, to a method for analyzing human mutant PAH activity by transforming a PAH gene, containing a phenylketonuria-related mutation, into cellular slime molds, followed by culture in the minimum essential medium lacking tyrosine, and then measuring the growth rate of the cellular slime molds.
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