首页>
外国专利>
USE OF CANAGLIFLOZIN AND DERIVATIVES THEREOF IN THE TREATMENT OF CANCER
USE OF CANAGLIFLOZIN AND DERIVATIVES THEREOF IN THE TREATMENT OF CANCER
展开▼
机译:卡格列净及其衍生物在癌症治疗中的应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
The use of canangliflozin and derivatives thereof in the treatment and prevention of cancer is disclosed. Said compounds have been previously determined to be selective sodium glucose transporter 2 (SGLT2) inhibitors useful in the treatment of diabetes with effects that are similar to metformin. Canagliflozin has now been determined to activate AMP-activated protein kinase (AMPK) and inhibit the growth of a range of cancers. Further to this, use of canagliflozin in combination with other chemotherapeutics has now been determined to give rise to increased anti-cancer activity.
展开▼