USE OF CROTON- OR CALOPHYLLUM-DERIVED PROANTHOCYANIDIN POLYMERS OR BOTANICAL EXTRACTS IN COMBINATION WITH RIFAXIMIN FOR THE TREATMENT OF DIARRHEA IN NON-HUMAN ANIMALS

摘要

Provided are combination therapy methods and uses for treating diarrhea, particularly malabsorption diarrhea, in neonatal, young and adult non-human animals, particularly for treating diarrhea resulting from microbial infection of the animals, with a therapeutically effective amount of a proanthocyanidin polymer from Croton lechleri, in either enteric or non-enteric form, in combination with a therapeutically effective amount of the antimicrobial agent rifaximin.