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A PROTEIN THAT CAN MANIPULATE THE CELL MEMBRANE POTENTIAL IN RESPONSE TO ELECTROMAGNETIC FIELD (EMF) STIMULATION, AND METHODS OF USE
A PROTEIN THAT CAN MANIPULATE THE CELL MEMBRANE POTENTIAL IN RESPONSE TO ELECTROMAGNETIC FIELD (EMF) STIMULATION, AND METHODS OF USE
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机译:可以响应电磁场(EMF)刺激而操纵细胞膜电位的蛋白质及其使用方法
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摘要
Disclosed herein is the identification of an ion channel protein that is can be remotely activated by non-invasive electro-magnetic fields and termed the electromagnetic perceptive gene (EPG) gene. Also provided herein is an isolated nucleic acid encoding the EPG, cDNA for the EPG, and an amino acid sequence encoding the EPG. Methods of isolation of the nucleic acid, protein, polypeptides and methods of making antibodies to the EPG are also provided. The use of the EPG in cells or populations of cells for modulation of cell function and excitability are also provided.
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