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BIOMARKERS FOR MALARIA DIAGNOSIS

机译:疟疾诊断的生物标记

摘要

Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.
机译:本文公开了通过检测来自受试者的样品中一种或多种代谢物的存在和/或量来检测受试者中的疟原虫(例如,疟原虫的存在)的方法。在一些实施方案中,该方法包括在样品中检测表1,表2和/或表5-8中列出的一种或多种代谢物。将样品中一种或多种代谢物的量与对照中一种或多种代谢物的量进行比较,如果一种或多种代谢物的量不同(例如,统计学上显着增加或减少),则确定是否存在疟原虫)相比。

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