The present invention relates to a pharmaceutical composition for the prophylaxis or treatment of an allergic disease comprising an anti-Siglec-8 antibody and / or an anti-Siglec-F antibody, and an anti-IL-33 antibody. The invention also relates to a food or cosmetic composition for the prevention or amelioration of an allergic disease comprising an anti-Siglec-8 antibody and / or an anti-Siglec-F antibody, and an anti-IL-33 antibody. The combined administration of the anti-Siglec-8 antibody and / or the anti-Siglec-F antibody and the anti-IL-33 antibody of the present invention is superior to the administration of the anti-Siglec-F antibody or the anti- Significant alleviation of allergic symptoms in sex-diseased animal models allows effective prevention and treatment of allergic diseases.
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