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Phase 1b Study of AK002, an Anti-Siglec-8 Monoclonal Antibody, in Patients with Severe Allergic Conjunctivitis (KRONOS Study)

机译：AK002的第1B期AK002，抗SigleC-8单克隆抗体，严重过敏性结膜炎的患者（Kronos研究）

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H. Terry Levine; Joseph Tauber; Quan Nguyen; Stephen Anesi; Peter Chang; Gregg Berdy; Charles Lin; David Chu; Andrea Kantor; Henrik Rasmussen; Bhupinder Singh; Alan Chang; Bennie Jeng; Vishal Jhanji; C. Stephen Foster;
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1. CLINICAL ACTIVITY OF AK002, AN ANTI-SIGLEC-8 ANTIBODY, IN SEVERE ALLERGIC CONJUNCTIVITIS AND COMORBID ATOPIC DISEASES [J] . Levine T., Tauber J., Nguyen Q., Annals of allergy, asthma, and immunology . 2019,第5Suppla1期

机译：AK002，抗Siglec-8抗体，严重过敏性结膜炎和合并症特应性疾病的临床活性
2. Phase 1b study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced melanoma (KEYNOTE-041) [J] . Yamazaki Naoya, Takenouchi Tatsuya, Fujimoto Manabu, Cancer chemotherapy and pharmacology. . 2017,第4期

机译：Pembrolizumab（MK-3475;抗PD-1单克隆抗体）的第1B期关于日本晚期黑素瘤（Keynote-041）的患者
3. Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study [J] . Brana Irene, Calles Antonio, LoRusso Patricia M., Targeted oncology . 2015,第1期

机译：Carlumab，一种抗C-C趋化因子配体2单克隆抗体，与四种化疗方案结合用于治疗实体瘤患者：一项开放性，多中心的1b期研究
4. A Humanised Anti-IL-17BR Monoclonal Antibody with Wide Therapeutic Potential in Allergic Asthma, Ulcerative Colitis, Pulmonary Fibrosis and Pancreatic Cancer [C] . Seema Patel, Carolina Fernes, Richard Brown, PEGS . 2015

机译：一种抗IL-17BR单克隆抗体，过敏性哮喘，溃疡性结肠炎，肺纤维化和胰腺癌中具有宽治疗潜力
5. Development and Characterization of Novel Anti-bat Monoclonal Antibodies for Studying Bat Immunity [D] . Cowan, Cailyn. 2017

机译：研究蝙蝠免疫的新型抗蝙蝠单克隆抗体的开发与表征
6. Phase 1b study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced melanoma (KEYNOTE-041) [O] . Naoya Yamazaki, Tatsuya Takenouchi, Manabu Fujimoto, -1

机译：pembrolizumab（MK-3475;抗PD-1单克隆抗体）在日本晚期黑色素瘤患者中的1b期研究（KEYNOTE-041）
7. A PHASE I, SINGLE-BLIND STUDY TO DETERMINE THE SAFETY, TOLERANCE, PHARMACOKINETICS AND PHARMACODYNAMICS OF ANTI-IgE RECOMBINANT HUMANIZED MONOCLONAL ANTIBODY E25 (rhu MAb-E25) IN ADOLESCENTS AND CHILDREN WITH MODERATE TO SEVERE ALLERGIC ASTHMA. 39 [O] . D Bisberg, J Froehlich, M Schoenhoff, 1996

机译：I阶段，单盲研究，以确定抗IgE重组人源化单克隆抗体E25（RHU mAb-E25）在青少年和中度至严重过敏性哮喘中的儿童中的安全性，耐受性，药代动力学和药效学和药效学。 39.
8. Monoclonal Antibodies and Cancer. Studies on the Use of Monoclonal Antibodies for Imaging and Therapy of Cancer, with Special Emphasis on Ovarian Carcinoma [R] . Haisma, H. J. 1987

机译：单克隆抗体和癌症。单克隆抗体在癌症成像和治疗中的应用研究，特别强调卵巢癌

Phase 1b Study of AK002, an Anti-Siglec-8 Monoclonal Antibody, in Patients with Severe Allergic Conjunctivitis (KRONOS Study)

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