7S-34-4.2.0-135--7- PROCESS FOR THE ENZYMATIC SYNTHESIS OF 7S-34-DIMETHOXYBICYCLO4.2.0OCTA-135-TRIENE-7-CARBOXYLIC ACID AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND SALTS THEREOF

摘要

The present invention relates to the enzymatic synthesis of compounds of formula (I) and their use in the addition salt synthesis of ibabradine using ibabradine and a pharmaceutically acceptable acid.