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NOVEL COMPOSITION FOR ENHANCING COGNITIVE FUNCTION OF ALZHEIMER'S PATIENTS

机译:新型组合物,可增强老年痴呆症患者的认知功能

摘要

The present invention relates to a pharmaceutical composition for improving cognitive functions of a patient with Alzheimers diseases and, more specifically, to a pharmaceutical composition comprising a ginsenoside-containing fraction derived from a fruit extract of steam-dried ginseng as an active ingredient for improving cognitive functions of a patient with an Alzheimers disease. According to an embodiment of the present invention, the ginsenoside Rd and Re-containing extract of the steam-dried ginseng fruit is capable of upregulating the expression of vesicular acetylcholine transporter (AChE) and choline acetyltransferase (ChAT) related to the improvement of cognitive functions of a patient with an Alzheimers disease, and penetrating a blood brain barrier. Therefore, the composition can be effectively used for improving cognitive functions of a patient with an Alzheimers disease.
机译:本发明涉及用于改善患有阿尔茨海默氏病的患者的认知功能的药物组合物,更具体地,涉及包含衍生自蒸干人参果实提取物的含人参皂苷级分作为用于改善认知的活性成分的药物组合物阿尔茨海默氏病患者的功能。根据本发明的一个实施方案,人参干燥的人参果实的人参皂苷Rd和含Re的提取物能够上调与改善认知功能有关的水泡乙酰胆碱转运蛋白(AChE)和胆碱乙酰基转移酶(ChAT)的表达。患有阿尔茨海默氏病并穿透血脑屏障的患者。因此,该组合物可以有效地用于改善患有阿尔茨海默氏病的患者的认知功能。

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