MICROORGANISM FOR METHIONINE PRODUCTION WITH IMPROVED METHIONINE SYNTHASE ACTIVITY AND METHIONINE EFFLUX

摘要

The present application relates to a recombinant microorganism that is optimized for the fermentative production of methionine and / or its derivatives, wherein in the recombinant microorganism, cobalamin-dependent methionine synthase activity and methionine efflux are promoted. This application is also c. Wherein the cobalamin-dependent methionine synthase activity and methionine efflux are promoted in a suitable culture medium comprising a fermentative source of carbon and a source of sulfur in said microorganism, and d. And recovering methionine and / or a derivative thereof from the culture medium. The present invention also relates to a method for optimizing fermentative production of methionine and / or a derivative thereof.