NOVEL FORMULATION OF CILOSTAZOL, A QUINOLINONE-DERIVATIVE USED FOR ALLEVIATING THE SYMPTOM OF INTERMITTENT CLAUDICATION IN PATIENTS WITH PERIPHERAL VASCULAR DISEASE

摘要

Disclosed is a pharmaceutical composition which is in a solid form and contains particulate cilostazol or a salt thereof, cellulose, a diluent, and a lubricant. The pharmaceutical composition shows an in vivo plasma profile for cilostazol of which the value of C_(24h)/C_(max) is greater than or equal to 0.25. Also disclosed is a method for producing the pharmaceutical composition.