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METHOD FOR PREDICTING TREATMENT EFFECTS OF EGFR INHIBITOR IN GLIOBLASTOMA

机译:预测胶质母细胞瘤中EGFR抑制剂治疗效果的方法

摘要

The present invention relates to a method for predicting an effectiveness of a treatment effect of a subject with respect to an epidermal growth factor receptor inhibitor. More specifically, when an EGFR copy number is measured in DNA extracted from a subject through a method based on a new generation sequencing (NGS) scheme, it is clarified that sensitivity with respect to a treatment effect of an EGFR inhibitor is significantly high according to the EGFR copy number. Accordingly, the method based on a new generation sequencing (NGS) scheme may be useful as a method for predicting an effectiveness of a treatment effect of a subject with respect to an EGFR inhibitor.
机译:本发明涉及一种预测对象对表皮生长因子受体抑制剂的治疗效果的有效性的方法。更具体地,当通过基于新一代测序(NGS)方案的方法测量从受试者中提取的DNA中的EGFR拷贝数时,可以清楚地看出,关于EGFR抑制剂的治疗效果的敏感性非常高。 EGFR拷贝数。因此,基于新一代测序(NGS)方案的方法可以用作预测受试者对EGFR抑制剂的治疗效果的有效性的方法。

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