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Method for Predicting Treatment Effects of EGFR Inhibitor in Glioblastoma

机译:预测胶质母细胞瘤中EGFR抑制剂治疗效果的方法

摘要

The present invention relates to a method for predicting the effectiveness of a therapeutic effect on an epidermal growth factor receptor (EGFR) inhibitor, and more particularly, the present invention relates to a method for predicting the efficacy of a new genome sequencing (NGS) (EGFR) copy number was measured in the DNA collected from the subject, and the sensitivity to the therapeutic effect of the EGFR inhibitor was significantly high according to the number of EGFR copies. Thus, the EGFR (epidermal growth factor receptor can be usefully used as a method for predicting the effectiveness of a therapeutic effect on a subject.
机译:本发明涉及预测对表皮生长因子受体(EGFR)抑制剂的治疗效果的有效性的方法,更具体地,本发明涉及预测新基因组测序(NGS)的有效性的方法(在从受试者收集的DNA中测量EGFR)拷贝数,并且根据EGFR拷贝数,对EGFR抑制剂的治疗效果的敏感性显着高。因此,EGFR(表皮生长因子受体)可以有效地用作预测对受试者的治疗效果的有效性的方法。

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