: Dissolution system of lipophilic drugs into biodegradable polymer: Smart Polymer System

摘要

The present invention relates to a biodegradable microstructure for the transdermal drug delivery containing a nanocolloidal particle formed by combination of a lipophilic drug and a biodegradable polymer. The present invention provides a biodegradable microstructure for homogenizing a lipophilic drug in a biodegradable polymer without using an organic solvent, and prepared by using the biodegradable polymer in which the lipophilic drug is homogenized. Therefore, the present invention will be a drug delivery system useful for a lipophilic drug without a suitable solvent, or with low bioavailability, or having a large molecular weight.