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BONE REGENERATING SUPPORT COATED WITH BONE-DERIVED EXTRACELLULAR MATRIX

机译:涂有骨源性细胞外基质的骨再生支持

摘要

The present invention relates to a bone regenerating support and a method for producing the same. The bone regenerating support comprises: a first layer including a biodegradable polymer; and a second layer wrapping the first layer and including a bone demineralized and decellularized extracellular matrix (bdECM). A bone regenerating support coated with an extracellular matrix can be produced through a 3D printer in a shape correctly corresponding to an affected area where bone damage occurs, and is rapidly coupled with an affected area compared to a conventional support. Also, deposition, proliferation, and bone differentiation of surrounding bone tissue cells are improved, so a more rapid bone generating effect can be expected. Moreover, a step like cell transplantation is not needed, so a support can be transplanted to a bone damage patient in a short time and more rapid recovery can be expected.;COPYRIGHT KIPO 2016
机译:骨再生支持体及其制造方法技术领域本发明涉及骨再生支持体及其制造方法。骨再生载体包括:第一层,其包括可生物降解的聚合物;和第二层。第二层包裹第一层并包括骨脱矿质和脱细胞的细胞外基质(bdECM)。涂覆有细胞外基质的骨再生支持物可以通过3D打印机生产,其形状正确对应于发生骨损伤的受影响区域,并且与常规支持物相比可以快速与受影响区域结合。而且,改善了周围骨组织细胞的沉积,增殖和骨分化,因此可以期望更快的骨生成效果。此外,不需要像细胞移植这样的步骤,因此可以在短时间内将支持物移植到骨损伤患者中,并有望更快恢复。; COPYRIGHT KIPO 2016

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