Methods and appratus for high-throughput label-free cell assay

摘要

the present invention is scanned by a broadband laser light source, the lower portion of the medium made of glass using a galvanometer mirror and the objective lens, using a spectrometer light coming back is reflected on the lower portion of the medium analyzing, imaging, but, spectrometer, the measured seupekteureomreul a light return is reflected at each interface forming interference medium glass, by measuring the phase at the interference seupekteureomreul Fourier transform measurement data for observing the structural change of the cell, high-power non- It relates to a cell analysis system markers. Jimyeo unlabeled cell analysis system of the present invention, a sample placed on, the bottom of a clear, transparent medium; It is located under the transparent medium, the objective lens; Is positioned below the objective lens, two by the mirror having the said, depending on the second rotation of the two mirrors, and emits the light incident through an optical fiber coupler from a broadband light source to the transparent medium through an objective lens, an objective lens from the transparent medium for emitting light returning through the optical coupler, the galvanometer mirror; Transmitting the incident light from the broadband light source to a galvanometer mirror, and transmits the light incident from the galvanometer mirror as spectroscopy, optical fiber coupler; But outputs the image to detect a spectrum of light incident from the optical fiber coupler, which, spectrometer output an image of the formed interference spectrum cause interference by the sample and the transparent medium; made including, the image of the interference spectrum, the objective lens doedoe through the light is reflected from the sample is incident to the transparent medium, characterized in that the image obtained by causing an interference by the boundary of the sample and the transparent medium. ;