Antimicrobial method by blocking manitol metabolism and Antimicrobial composition containing mannitol metabolic inhibitor

摘要

The present invention relates to an antibacterial method for sterilizing a bacterium having a mannitol metabolism pathway through inhibition of mannitol metabolism, a method for screening a mannitol metabolism inhibitor, and a composition and a cosmetic for antimicrobial composition containing a mannitol metabolism inhibitor. More specifically, An inhibitor screening method and composition targeting a mannitol metabolizing enzyme such as mannitol-1-phosphate-5-dehydrogenase (M1PDH). INDUSTRIAL APPLICABILITY According to the present invention, it is possible to provide an antibacterial method, a composition for antimicrobial use and a cosmetic composition which solve the problem of antibiotic resistance and have an excellent antibacterial effect.