probes kits and methods for detecting mutation of filaggrin gene

摘要

The invention pillar green (filaggrin) mutation to a nucleic acid sequence on the probe and the pillar green gene mutation detection method using the same coupling complementarily, specifically complementarily coupled to the pillar green gene by preparing a PNA probe and provide the convenience of simply and quickly and accurately determine the pillar green genetic mutation using the FMCA using difference between binding affinity of the wild type and mutant type, can be diagnosed pathological factors of atopic dermatitis patients become that and it may be particularly likely to quickly diagnose the onset of atopic dermatitis in infants born after the period directly decreases the incidence ;