MATRIX FOR IONIZING N-GLYCAN SAMPLE, METHOD FOR MANUFACTURING SAME, AND METHOD FOR MASS SPECTROMETRY USING SAME

摘要

A matrix for ionizing a sample including N-glycan may comprise: N,N-diisopropylethyl (DIEA), α-cyano-4-hydroxycinnamic acid (CHCA), ammonium dihydrogen phosphate (ADP), and sodium chloride. When a sample is analyzed by a matrix-assisted laser desorption/ionization time-of- flight (MALDI-TOF) method by using the matrix, there are advantages in which signal homogeneity is high, linearity of intensity relative to concentration of an analysis sample is excellent, reproducibility of intensity between MALDI spots is high, and intensity of ionization of N-glycan increases and matrix noise decreases, compared to those of a conventional technology.;COPYRIGHT KIPO 2016