CAGE Compositions for overcoming anti-cancer drug-resistance or compositions for anti-cancer activity employing CAGE-derived peptides

摘要

The present invention relates to a pharmaceutical composition for reducing anticancer resistance of cancer cells containing an oligopeptide derived from CAGE as an active ingredient, and more particularly to a pharmaceutical composition for anticancer drug resistance comprising an oligopeptide of SEQ ID NO: 1 or SEQ ID NO: 2 derived from CAGE as an active ingredient To a pharmaceutical composition which reduces the anticancer drug resistance of cancer cells or exhibits an anticancer effect. The pharmaceutical composition of the present invention can effectively reduce the anticancer drug resistance of cancer cells or cancer tissues resistant to the anticancer drug, thereby enhancing the therapeutic effect using the anticancer drug. In addition, the pharmaceutical composition of the present invention has excellent anticancer activity . The oligopeptide, which is an effective component of the pharmaceutical composition of the present invention, has an advantage that it has a small molecular weight and has little fear of an immune reaction and is easy to penetrate into tissues and can act selectively on cancer cells or cancer tissues, It can be said that it can be effectively improved.