Microfluidic system manufacturing method thereof and method of cell encapsulation in hydrogel

摘要

The present invention relates to a technique of supporting cells on a hydrogel, and more particularly, to a microfluidic device in which fine cells are dispersed in a single cell while passing through a fine columnar array zone and a focusing zone and supported on a hydrogel, To a method of supporting cells on a gel. By applying the cell carrying method using the microfluidic device according to the present invention, microorganism cells that are not spherical aggregated are dispersed by using a structure called a micropillar array zone, and the droplets are carried in the form of single cells in hydrogel drops in a focusing zone, It is possible to solve the problem of cell aggregation due to the polymer and to carry the separated cells in the form of a single cell in a hydrogel.