High-throughput screening system for inhibitor against pathogenicity of enterohemorrhagic or enteropathogenic Escherichia coli and recombinant Escherichia coli being used for the same

摘要

The present invention relates to a high-speed search system capable of searching pathogenic inhibitors of pathogenic Escherichia coli through the search for a substance specifically inhibiting Ler protein, a recombinant Escherichia coli used in the high-speed search system, and a method for producing the same. , The pathogenic inhibitor of pathogenic Escherichia coli which can minimize the incidence of resistant bacteria by selectively inhibiting pathogenic properties such as biofilm formation ability and adherence ability of human colon cells without inhibiting the growth of pathogenic Escherichia coli, It is possible to search.