首页> 外国专利> METHOD FOR INDUCING CELL DEATH IN PLURIPOTENT STEM CELLS AND DIFFERENTIATED CELLS OTHER THAN CARDIAC MYOCYTES

METHOD FOR INDUCING CELL DEATH IN PLURIPOTENT STEM CELLS AND DIFFERENTIATED CELLS OTHER THAN CARDIAC MYOCYTES

机译:在除心肌细胞外的多能干细胞和分化细胞中诱导细胞死亡的方法

摘要

It is possible to induce apoptosis in pluripotent stem cells such as embryonic stem cells or inducible pluripotent stem cells and pluripotent stem cells derived from multipotent stem cells without genetic modification, The problem is to develop a method. The present invention relates to a method for inducing apoptosis in cells other than myocardial cells by adding a substance which is not recognized as a material toxicity or apoptosis inducing action to the culture conditions of pluripotent stem cells or non-myocardial cells, The above problem can be solved without modifying the gene.;
机译:可以在不进行基因修饰的情况下诱导多能干细胞例如胚胎干细胞或诱导型多能干细胞和衍生自多能干细胞的多能干细胞的凋亡。问题是开发一种方法。本发明涉及一种通过在多能干细胞或非心肌细胞的培养条件中添加未被认为具有物质毒性或凋亡诱导作用的物质来诱导心肌细胞以外的细胞凋亡的方法,上述问题可以解决。无需修饰基因即可解决。

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